Overview
Flatiron Health, a subsidiary of the Roche Group, is a premier health-tech firm specializing in oncology-specific software and data solutions. By 2026, it has solidified its position as the industry leader in transforming unstructured clinical information into research-grade Real-World Data (RWD). The core of its technical architecture is OncoEMR, a cloud-native Electronic Health Record (EHR) system used by thousands of community oncologists. Flatiron leverages advanced Machine Learning and expert clinical abstraction to process clinician notes, pathology reports, and genomic data into longitudinal datasets. These datasets enable pharmaceutical companies to generate Real-World Evidence (RWE) for regulatory submissions, post-market surveillance, and clinical trial design. The 2026 ecosystem emphasizes interoperability via HL7 FHIR standards and deep integration with molecular diagnostic providers. Their 'Flatiron Assist' tool provides real-time clinical decision support, ensuring that providers are aligned with the latest NCCN Guidelines while simultaneously capturing structured data that fuels the next generation of cancer therapies. It is a critical infrastructure component for precision medicine, bridging the gap between daily clinical practice and large-scale academic research.