FSL - FMRIB Software Library

Preprocess the FMRI data using FSL's preprocessing tools.

Perform statistical analysis using FSL's GLM module.

Create a contrast to compare brain activity during the visual stimulus with a baseline condition.

Threshold the statistical map to identify significant brain activation.

Visualize the activated brain regions using FSLView.

Process the diffusion MRI data using FSL's diffusion tools.

Calculate DTI metrics such as fractional anisotropy (FA) and mean diffusivity (MD).

Compare DTI metrics between patients and healthy controls.

Identify regions with significantly reduced FA or increased MD.

Correlate DTI metrics with clinical measures of disease severity.

Preprocess the resting-state FMRI data.

Perform independent component analysis (ICA) using FSL's MELODIC module.

Identify resting-state networks (RSNs) based on the ICA results.

Calculate functional connectivity between RSNs.

Compare functional connectivity patterns between different groups or conditions.

Preprocess the FMRI data for each subject.

Perform first-level statistical analysis for each subject.

Perform group-level statistical analysis using FSL's FEAT module.

Create a contrast to test for group-level effects.

Threshold the statistical map to identify significant brain activation.

Acquire MRI scans at multiple time points for each subject.

Preprocess all MRI scans consistently.

Register the scans to a common template space to account for anatomical differences.

Perform statistical analyses to detect significant changes in brain volume, activity, or connectivity over time.

Visualize and interpret the longitudinal changes using FSL tools.