NeuroPace RNS System

The NeuroPace RNS System is a sophisticated, cranially implanted neurostimulator designed for patients with medically refractory focal epilepsy. As of 2026, the system represents a paradigm shift in personalized neurology, utilizing advanced detection algorithms and machine learning to provide real-time, responsive therapy. Unlike traditional Vagus Nerve Stimulation (VNS) or Deep Brain Stimulation (DBS) which deliver scheduled pulses, the RNS System monitors intracranial electroencephalogram (iEEG) activity 24/7. When the system's AI-driven detection engine identifies a patient-specific seizure-onset pattern, it delivers imperceptible electrical pulses to disrupt the activity before clinical symptoms occur. The system integrates with the NeuroPace nSight Platform (formerly PDMS), a cloud-based data management system that allows clinicians to analyze years of longitudinal neural data. This capability enables precision medicine by correlating seizure frequency with lifestyle factors, medication changes, and circadian rhythms. The 2026 iterations include enhanced MRI compatibility (1.5T/3T) and extended battery longevity, positioning it as the gold standard for data-driven epilepsy management in the digital health era.