Reactome

Step 1: Search for cancer-related pathways in Reactome.

Step 2: Visualize the pathway of interest using the Pathway Browser.

Step 3: Identify key proteins or reactions within the pathway.

Step 4: Research potential drug candidates that target these proteins or reactions.

Step 1: Upload gene expression data to the 'Analyse gene expression' tool.

Step 2: Run the analysis to identify enriched pathways.

Step 3: Examine the results to determine which pathways are most significantly affected.

Step 4: Investigate the affected pathways using the Pathway Browser.

Step 1: Search for the drug of interest in Reactome.

Step 2: Identify the pathways that the drug interacts with.

Step 3: Visualize the pathways using the Pathway Browser.

Step 4: Examine the reactions and molecules involved in the drug's mechanism of action.

Step 1: Use the Species Comparison tool to compare pathways between species.

Step 2: Select the species of interest.

Step 3: Identify pathways that are conserved or divergent.

Step 4: Analyze the differences and similarities in pathway components.

Step 1: Search for disease-related pathways in Reactome.

Step 2: Identify proteins or molecules that are highly expressed or modified in the disease.

Step 3: Validate these proteins or molecules as potential biomarkers.

Step 4: Develop assays to measure these biomarkers in patient samples.