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Home/Tasks/SWISS-MODEL
SWISS-MODEL logo

SWISS-MODEL

SWISS-MODEL is a fully automated protein structure homology-modelling server accessible via the Expasy web server.

LearningAPI available
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Predicting 3D structures of proteins based on sequence homologyIdentifying suitable template structures for homology modeling
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About SWISS-MODEL

SWISS-MODEL is a fully automated protein structure homology-modeling server designed to make protein modeling accessible to life science researchers worldwide. It leverages comparative modeling techniques to predict 3D structures of proteins based on the known structures of homologous proteins (templates). The server automatically searches for suitable templates, builds models, and assesses their quality. Recent updates include the integration of AlphaFoldDB structures as templates and an API for accessing OpenStructure actions. SWISS-MODEL is developed by the Computational Structural Biology Group at the SIB Swiss Institute of Bioinformatics and the Biozentrum of the University of Basel and is an ELIXIR Core Data Resource. Users can submit protein sequences to the SWISS-MODEL server, and the system returns predicted 3D structures along with quality estimates, providing a valuable resource for structural biology research and drug discovery.

Core Capabilities

SWISS-MODEL is a fully automated protein structure homology-modeling server designed to make protein modeling accessible to life science researchers worldwide.

Main Tasks

Predicting 3D structures of proteins based on sequence homology

Explore all tools that specialize in predicting 3d structures of proteins based on sequence homology. This domain focus ensures SWISS-MODEL delivers optimized results for this specific requirement.

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Identifying suitable template structures for homology modeling

Explore all tools that specialize in identifying suitable template structures for homology modeling. This domain focus ensures SWISS-MODEL delivers optimized results for this specific requirement.

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Automating the protein structure modeling process

Explore all tools that specialize in automating the protein structure modeling process. This domain focus ensures SWISS-MODEL delivers optimized results for this specific requirement.

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Assessing the quality of generated protein models

Explore all tools that specialize in assessing the quality of generated protein models. This domain focus ensures SWISS-MODEL delivers optimized results for this specific requirement.

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Providing access to a repository of pre-computed protein models

Explore all tools that specialize in providing access to a repository of pre-computed protein models. This domain focus ensures SWISS-MODEL delivers optimized results for this specific requirement.

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Facilitating research in structural biology and drug discovery

Explore all tools that specialize in facilitating research in structural biology and drug discovery. This domain focus ensures SWISS-MODEL delivers optimized results for this specific requirement.

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Decision Summary

What this tool is best suited for

Best Fit
BioinformaticsScientific Research
Buying Signals
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API available
Web-first workflow
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Core Tasks

  • Predicting 3D structures of proteins based on sequence homology
  • Identifying suitable template structures for homology modeling
  • Automating the protein structure modeling process
  • Assessing the quality of generated protein models
  • Providing access to a repository of pre-computed protein models
  • Facilitating research in structural biology and drug discovery

Target Personas

BioinformaticsScientific Research

Categories

Learning3D & Modeling

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